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Revitalize Your Skin: The Science Behind Biostimulator Injections with Radiesse®, Sculptra®, PROFHILO® and HArmonyCa®

Jonathan J. Redeker, MD

June 24, 2024

What are biostimulators?

In the search for timeless beauty, biostimulators have proven to be a revolutionary solution. Biostimulation therapies are versatile and include injectable biostimulators, needling, threads, exosomes and stem cells. This blog is exclusively about ready-to-use injectable biostimulators, with more exciting content on other types coming soon!

Join us as we reveal the remarkable potential of some of the most popular ready-to-use injectable biostimulators for skin rejuvenation to deliver a natural, long-lasting skin glow.

What can injectable biostimulators do for you?

Injectable biostimulators can be used on all skin types, whether young or mature, dry, stressed or oily, and also on acne-prone skin. They improve skin hydration, firmness and elasticity, refine texture and shrink pores. Various skin problems such as wrinkles, acne scars, enlarged pores, stretch marks and cellulite can be effectively treated.

Falten

Biostimulators are designed to combat wrinkles by reducing fine lines and wrinkles on the face. At the same time, they can improve skin volume and the smoothness of the skin surface.

Volumenverlust

The aging process often leads to a reduction in volume in certain areas of the face, resulting in a tired appearance. Biostimulators can restore lost volume and revitalize the face to give it a youthful, refreshed appearance.

Festigkeit, Textur und Hautqualität

Biostimulators help improve skin firmness and elasticity, refine texture and smooth out irregularities caused by sun damage. By increasing skin moisture and reducing the visibility of pores, biostimulators further improve the overall quality of the skin.

Cellulite

Cellulite is an unattractive and incurable disease of the skin and subcutaneous tissue that affects more than 90% of Caucasian women. Biostimulators can reduce dents, tighten and strengthen the skin and thus improve the typical “orange peel” of the affected areas.

Narben

Biostimulators can be used successfully to treat scars caused by acne or minor skin injuries and ensure a more even complexion.

How does the treatment work?

Injectable biostimulators are generally administered into the deep layer of the skin or just under the skin. They work differently than hyaluronic acid and primarily activate the body’s production of important proteins such as collagen and elastin, which naturally decreases with age. These compounds are the building blocks for tissue regeneration, a process that results in improved skin texture, fewer wrinkles, and a more elastic, youthful appearance.


Körpereigene Regeneration

Unlike traditional fillers that primarily add volume, injectable biostimulators promote the skin’s natural ability to regenerate its own structure. The biostimulators, for which a number of different products are available, are a sophisticated approach to revitalizing the skin and achieving long-lasting results.

Radiesse®


Radiesse® is a long-proven product for tissue regeneration. It is designed to increase skin volume and relieve wrinkles and volume loss on the face or a variety of other areas of the body. Thanks to newer techniques, it can now be used as a pure biostimulator, without the immediate volume effect and associated risks of a non-reversible, long-lasting filler. Radiesse® differs from typical fillers in that it stimulates the tissue to produce fresh collagen, which is not the case with typical hyaluronic acid fillers. This particularly efficient process not only revitalizes the skin by building volume, but also tightens sagging skin and reduces wrinkles.

After injection, Radiesse immediately initiates the formation of a subcutaneous “scaffold” while activating the body’s own collagen production. Radiesse® consists of calcium hydroxyapatite (CaHa), which is suspended in a gel matrix and is metabolically broken down during absorption, leading to the activation of regeneration processes. Multiple treatments are often required to achieve optimal results.

The results of facial and body treatments are usually good and the risk of complications is minimal when performed by specialized professionals, such as a plastic surgeon. The results usually last about 1-2 years. Radiesse® can be used as a pure biostimulator (hyperdilute) or as a combined filler and biostimulator. In aging hands, it is optimally introduced in a less diluted form into the subcutaneous layer of the back of the hand to increase volume and reduce the visibility of veins and tendons and improve skin quality. After the treatment, you can expect slight swelling for about three days.

Sculptra®


Sculptra® is another ready-to-use biostimulator that can give you a rejuvenated look. Like Radiesse®, it works by increasing natural collagen production in your body.

The effect of Sculptra® also develops gradually. This is due to its composition of poly-L-lactic acid, a biocompatible substance that produces a beneficial inflammatory response in the tissue, thus promoting regenerative processes. The increased collagen production improves the texture and elasticity of the skin, resulting in a youthful and radiant complexion.

For optimal results, multiple treatments are required four to six weeks apart. It’s typical to experience swelling for a few days, followed by a period where little changes. You may notice a slight difference approximately six to eight weeks after the first session. Results continue to improve until approximately six months after the last treatment. We recommend at least three treatment sessions.

PROFHILO®


PROFHILO® is a unique product among injectable biostimulators because it contains only highly pure hyaluronic acid and still stimulates collagen and elastin production, whereas the hyaluronic acid technologies in products such as Restylane or Juvéderm do not primarily do this. PROFHILO® does not work like a filler. Although the technology is quite different, it is more similar to hyaluronic acid-based hydrating products such as Volite and Restylane Vital, which are used for mesotherapy. In addition to stimulating collagen and elastin through the slow release of hyaluronic acid (tightening and firming the skin), the product draws water into the deeper layers of the skin, giving the skin a plump and hydrated appearance.

HArmonyCa®


This innovative dual-action hybrid injectable combines two powerful skin rejuvenation ingredients, hyaluronic acid (HA) and CaHa, to provide both an immediate lifting effect and long-lasting tissue improvement.

The special thing about HArmonyCa® is its hybrid technology. The HA with its networked structure provides an immediate lifting effect that eliminates wrinkles and lines

smoothes, while CaHa acts as a biostimulator and revitalizes and tightens the facial skin over time.

HArmonyCa® is aimed at people who are concerned about age-related loss of facial structure and are seeking a lasting improvement in facial proportions, as well as improving skin texture and reducing lines and wrinkles.

Transformative Vorteile


Are you ready to experience the transformative benefits of biostimulator injections? Contact us today to receive personal information and to schedule a consultation.


Discover how injectable biostimulators can rejuvenate your skin and enhance your natural beauty!